Association of rs1800624 Polymorphism in Receptor for Advanced Glycation End Products Gene Promoter with the Risk of Diabetic Nephropathy
نویسندگان
چکیده
Association of rs1800624 Polymorphism in Receptor for Advanced Glycation End Products Gene Promoter with the Risk Diabetic Nephropathy
منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولAdvanced glycation end-products in diabetic nephropathy
Throughout the industrialized (well-fed) Adverse effects of hyperglycaemia, once thought an epiphenomenon in the pathogenesis of diabetic microworld, diabetes mellitus is the most prevalent cause of end-stage renal disease (ESRD). Diabetic nephropathy and macrovascular complications, presently are a central focus of active clinical and basic investigation is as likely to develop in long-duratio...
متن کاملAdvanced glycation end products and diabetic nephropathy.
Chronic hyperglycemia and oxidative stress in diabetes results in the formation and accumulation advanced glycation end products (AGEs). AGEs have a wide range of chemical, cellular, and tissue effects that contribute to the development of microvascular complications. In particular, AGEs appear to have a key role in the diabetic nephropathy. Their importance as downstream mediators of tissue in...
متن کاملAssociation of genetic variants in the receptor for advanced glycation end products gene with diabetic retinopathy
BACKGROUND Diabetic retinopathy (DR) is a major sight-threatening diabetic complication. Previous studies have examined the association of DR with multiple genetic variants in the receptor for advanced glycation end products (RAGE) gene, with inconsistent results. OBJECTIVE To perform a systematic literature search and conduct meta-analyses to examine the association of genetic variants in RA...
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Diabetic nephropathy is a life-threatening complication of diabetes mellitus and the leading cause of end-stage renal disease (ESRD) in developed countries. Diabetes is responsible for over 40% of all new cases with ESRD in the United States and Japan, eventually undergoing renal dialysis or transplantation. Diabetic nephropathy is characterized by glomerular hyperfiltration and thickening of g...
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ژورنال
عنوان ژورنال: Scientific journal of Kurdistan University of Medical Sciences
سال: 2022
ISSN: ['1560-652X', '2345-4040']
DOI: https://doi.org/10.52547/sjku.27.3.1